Biography
Biography: Heyam Saad Ali
Abstract
During the early sixties, drug product development was at its peak and soon afterwards, many new products were introduced. Some of these new chemical compounds exhibited variations in their pharmacologic and therapeutic activity This led to the recognition of the fact that a great deal of knowledge is required for studying the many factors that affect the bioavailability of the administered drug. The term bioavailability is defined as the rate and extent of the active ingredient (s) in the biological system. This movement of the drug is influenced by many factors such as including routes of administration, physicochemical drug properties, physiological factors, methods & techniques used in manufacture, the dosage form into which the drug incorporated and the excipients such as bulking agents, binders, lubricants, dyes, disintegrants, coating materials, etc.). Hence these factors may require special consideration in determining bioavailability of the
active ingredient from the dosage form.
During the early sixties, drug product development was at its peak and soon afterwards, many new products were introduced. Some of these new chemical compounds exhibited variations in their pharmacologic and therapeutic activity This led to the recognition of the fact that a great deal of knowledge is required for studying the many factors that affect the bioavailability of the administered drug. The term bioavailability is defined as the rate and extent of the active ingredient (s) in the biological system. This movement of the drug is influenced by many factors such as including routes of administration, physicochemical drug properties, physiological factors, methods & techniques used in manufacture, the dosage form into which the drug incorporated and the excipients such as bulking agents, binders, lubricants, dyes, disintegrants, coating materials, etc.). Hence these factors may require special consideration in determining bioavailability of the active ingredient from the dosage form.