Fundamentals of Bioavailability and Bioequivalence Studies

The fundamentals of bioavailability and bioequivalence studies lie in understanding how drugs are absorbed, distributed, metabolized, and excreted within the body. Bioavailability refers to the rate and extent to which a drug reaches systemic circulation, whereas bioequivalence compares the pharmacokinetic parameters of a test drug to that of a reference drug. These studies are crucial in pharmaceutical development to ensure the safety, efficacy, and interchangeability of generic drugs with their brand-name counterparts

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